Butabarbital decreases consequences of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Coadministration of CYP3A4 inducers may well minimize sufentanil concentrations and efficacy, perhaps precipitating withdrawal syndrome in patients who have created physical dependence to sufentanil. Discontinuation of concomitantly utili... https://jacquesu786all3.blogscribble.com/profile